Program

3rd ITALIAN ZEBRAFISH MEETING

1st DAY - February, 9

12:00: Opening registration

13:30: Welcome and opening addresses

AFTERNOON SESSION

Development

14.00 – 14.15: Cell dynamics underlying the 3D organization of the zebrafish statoacoustic ganglion - A. Bañón, University Pompeu Fabra
14.15 – 14.30: Plasticity in retinal lineage decisions results in tissue robustness - E. Nerli - Instituto Gulbenkian de Ciência and Max Planck institute for Molecular Cell Biology and Genetics
14.30 – 14.45: Neuropilin 1 mainly acts as a mediator of chemorepulsive cues during zebrafish trunk vascularisation - E. Guzzolino, University of Milan and Meyer Children's Hospital
14.45 – 15.00: The stimulatory effect of the synthetic sulfolipid Sulfavant A on zebrafish microglia - V. Nittoli, Biogem Institute of Molecular Biology and Genetics
15.00 – 15.15: Zebrafish scarb2a knockout reveals a novel role for endo-lysosomal machinery during neurovascular development - I. Bassi, Weizmann Istitute of Science
15.15 – 15.30: Neurovascular Interaction in Sensory Neuron Development - B. Alsina Espanol, Universitat Pompeu Fabra
15.30 – 15.45: MiR-204 is required for photoreceptor rod differentiation and maturation - G. Giamundo, Telethon Institute of Genetics and Medicine
15.45 – 16.15: Coffee Break
16.15 – 16.30: Standard and custom-made behavioral monitoring solutions for Zebrafish - A. Barbot, Viewpoint Behavior Technology

Neurobiology

16.30 – 16.45: Numerical discrimination by Archerfish - D. Potrich, University of Trento, Rovereto
16.45 – 17.00: Exploring the sense of number in zebrafish: a neurobiological approach - A. Messina, University of Trento, Rovereto
17.00 – 17.15: Evolution of Adult Neurogenesis (ANG): a comparative study on Chondrichthyes as basal Vertebrates - E. Terzibasi Tozzini, Stazione Zoologica Anton Dohrn
17.15 – 17.30: Glucosyl-Sterols as novel signaling molecules in the nervous system: role in physiology and pathology - F. Terrin, University of Padua
17.30 – 17.45: Ontogenetic changes of D-Asp in the brain of Nothobranchius furzeri - A. Palladino, University of Naples Federico II
17.45 – 18.00: Role of the BDNF in the zebrafish circadian system - E. Frigato, University of Ferrara

18:O0 - 19:00: Poster session

2nd DAY - February, 10

09:00 - 10:00: Keynote Lecture

Prof.Dr. Joachim Wittbrodt, Heidelberg University

MORNING SESSION

Emerging Technologies

10:00 – 10.15: A high-throughput system for Quality Control of Cas9 variants - F. De Santis, ZeClinics
10:15 – 10.30: Disease modelling by efficient genome editing using a near PAM-less base editor in vivo - F. Del Bene, Inserm
10:30 – 11.00: Coffee Break
11.00 – 11.15: InterZebTEC: a novel approach to the environmental microbiological monitoring of Zebrafish - T. Sala, Tecniplast

Disease Models

11.15 – 11.30: In vivo observation and modelling of the propagation of a neurotropic virus in zebrafish larvae and the role of type I interferons 11 - V. Laghi, Institut Pasteur
11.30 – 11.45: TERRA is overexpressed in ALT brain tumors and induces the activation of the RNA sensing pathway - M. Mione, University of Trento
11.45 – 12.00: The Interphotoreceptor matrix: investigating the role of IMPG2 in zebrafish retinal development and function - M.E. Castellini, University of Trento
12.00 – 12.15: Targeting Hedgehog and HDAC6 in acute myeloid leukemia in in vitro and zebrafish models - A. Pezzotta, University of Milan
12.15 – 12.30: An in-vivo zebrafish model with cecr1b deficiency recapitulates human DADA2 phenotypes - A. Brix, University of Milan
12.30 – 12.45: Dissecting mechanisms involved in the pathogenesis of Duchenne Muscular Dystrophy - M. Schiavone, University of Brescia

12:45 - 14:00: Lunch

AFTERNOON SESSION

14.00 – 14.15: Morphofunctional characterization of a novel zebrafish polg2 mutant line modelling POLG-related disorders - R. Brañas Casas, University of Padua
14.15 – 14.30: Automated high-content drug screening in zebrafish xenografts identifies effective combination treatments against Ewing sarcoma - A. Grissenberger, St. Anna Children's Cancer Research Institute
14.30 – 14.45: Insight CLN8: Approaching therapies in the neuronal ceroid lipofuscinoses, using Zebrafish as a Tool - M. Marchese, IRCCS Fondazione Stella Maris
14.45 – 15.00: Signalling pathways dysregulation in zebrafish Foetal Growth Restriction models with cardiovascular changes: drug treatment implications - G. Risato, University of Padua
15.00 – 15.15: Zebrafish as a functional model to assess the effects of Extracellular Vesicles on innate immune response modulation - M. Cafora, University of Milan
15.15 – 15.30: Zebrafish as animal model for melanoma research: analysis of coding and non-coding BRAFV600E variants - R. De Paolo, CRL-ISPRO and IFC-CNR
15.30 – 16.00: Coffee Break
16.00 – 16.15: Relevance of ATM dependent regulation of autophagy in Ataxia Telangiectasia – C. Gabellini, University of Pisa
16.15 – 16.30: Mutations in the new disease-causing gene ARF3 have disruptive consequences on Golgi integrity and brain development - A. Lauri, Ospedale Pediatrico Bambin Gesù
16.30 – 16.45: New insights into mitochondrial disorders: AKAP1 conditional knockout model in neuroendocrine system of zebrafish - C. Reale, Biogem Institute of Molecular Biology and Genetics
16.45 – 17.00: Zebrafish larva as a powerful model to illuminate Legionella pneumophila infection in vivo - E. Colucci–Guyon, Institut Pasteur

17:00 - 19:00: Poster session

3rd DAY - February, 11

09:00 - 10:00: Keynote Lecture

Prof. Karina Yaniv, Weizmann Institute of Science - Israel

MORNING SESSION

Metabolism

10.00 – 10.15: The role of GR, MR and STAT3 interplay in the regulation of mitochondrial metabolism - A. Tesoriere, University of Padua
10.15 – 10.30: The role of the mevalonate pathway in endothelial cells and angiogenesis process - M. Donadon, University of Padua
10.30 – 10.45: Quantifying zebrafish behavior. Solutions for research across the lifespan from embryo to adult - C. Tetteroo, Noldus Information Technology
10.45 – 11.15: Coffee Break

Toxicology, Drug Screening, Aquaculture

11.15 – 11.30: Intravitreal administration of rhNGF enhances regenerative processes in a zebrafish model of retinal degeneration - F. Cocchiaro, Dompé Farmaceutici
11.30 – 11.45: Evaluation of innovative radiotherapy treatments in zebrafish - G. Pucci, University of Palermo
11.45 - 12.00: Embryonic and larval exposure to propylparaben induces developmental and long-term neurotoxicity in the zebrafish model - C. Merola, University of Teramo
12.00 – 12.15: Caulerpin: a modulator of fish reproduction from a highly invasive species - V. Schiano, University of Naples Federico II
12.15 – 12.30: Polyphenols show anti-inflammatory effects on intestinal inflammation in zebrafish (Danio rerio) - G. Orso, University of Sannio
12.30 – 12.45: Zebrafish, a successful tool for Aquaculture research - C. Sangiacomo, University of Pisa

12:45 - 13:30: Closing Remarks